The
race to decode the human genome is nearing its end, with several companies
and federally-backed research labs looking to lock up as many genes
as possible. No matter who finishes first, the real winner in this
contest may be the PE Corporation, which makes the automated genetic
"sequencers" high-powered machines that can analyze DNA at
a rate far faster than any human researcher that are the H-bombs
of this particular arms race. PE has sold 200 of the $300,000 machines
to NIH- associated labs and 300 to the leader in the race,
Celera, which is a division of, you guessed it, PE.
Patent concerns aside, this race may really be just beginning.
The cutting edge researchers believe the really important discoveries
won't come from looking at linear strands of genes but from examining
the interaction between dozens of genes at once. Scientists could
in theory use "biochips," arrays of hundreds of bits of your DNA
placed in a silicon wafer, to examine how how a drug would interact
with your particular biochemistry.
This could eliminate all those "some people reported nausea, vomiting,
blurred vision and extreme paranoia" disclaimers in pharmaceutical
ads. In the end, there's not one Human Genome Project -- there's
4.5 billion.
from
TIME
The
Race Is Over
The great genome quest is officially a tie, thanks to a
round of pizza diplomacy. Yet lead researcher Craig Venter still
draws few cheers from his colleagues
JULY 3, 2000
Life's
Twisted Plotline
DNA is like a book
FEBRUARY 28, 2000
The
Gene Machine
To the consternation of his rivals, Craig Venter may have the human
DNA 100% mapped by summer
JANUARY 25, 2000
The
TIME 100: James Watson and Francis Crick
MARCH, 1999
DNA
Mapping: Light at the End of the Tunnel
The human genome will be fully decoded in a matter of years
JANUARY 11, 1999
Craig
Venter
The man in a big hurry to map genes
JANUARY 11, 1999
On
the Horizon
Tissue factories; food as drugs; anti-aging; beyond vaccination
JANUARY 11, 1999
The
Worm is Learned
Biologists make the first listing of an animal's entire genome.
The subject? A microscopic roundworm called Caenorhabditis elegans.
DECEMBER 11, 1998